Oxygen therapy for acutely ill medical patients: a clinical practice guideline (2024)

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  3. Oxygen therapy for acutely ill medical patients: a clinical practice guideline

Practice Rapid Recommendations BMJ 2018; 363 doi: https://doi.org/10.1136/bmj.k4169 (Published 24 October 2018) Cite this as: BMJ 2018;363:k4169

Overview of recommendations

Recommendation 1 - upper limit

Comparison of benefits and harms

Recommendation 2 - lower limit (90-92%)

Recommendation 3 - lower limit (>92%)

Comparison of benefits and harms - patients with stroke

Comparison of benefits and harms - patients with myocardial infarction

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  1. Reed A C Siemieniuk, methods co-chair, general internist1,
  2. Derek K Chu, general internist2,
  3. Lisa Ha-Yeon Kim, clinical fellow2,
  4. Maria-Rosa Güell-Rous, senior pulmonology consultant3,
  5. Waleed Alhazzani, critical care clinician12,
  6. Paola M Soccal, pulmonologist45,
  7. Paul J Karanicolas, associate professor of surgery6,
  8. Pauline D Farhoumand, general internist7,
  9. Jillian L K Siemieniuk, registered nurse8,
  10. Imran Satia, respiratory physician2,
  11. Elvis M Irusen, professor of pulmonology and intensive care9,
  12. Marwan M Refaat, cardiologist10,
  13. J Stephen Mikita, patient partner11,
  14. Maureen Smith, patient partner12,
  15. Dian N Cohen, patient partner13,
  16. Per O Vandvik, general internist14,
  17. Thomas Agoritsas, general internist1715,
  18. Lyubov Lytvyn, patient partnership liaison1,
  19. Gordon H Guyatt, chair, distinguished professor12
  1. 1Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton L8S 4K1, Canada
  2. 2Department of Medicine, McMaster University, Hamilton L8S 4K1, Canada
  3. 3Departament de Pneumologia, Hospital de la Santa Creu I Sant Pau. Barcelona, Catalonia 08041, Spain
  4. 4Division of Pulmonary Medicine, Geneva University Hospitals, 1211 Geneva, Switzerland
  5. 5Faculty of Medicine, Geneva University, 1206 Geneva, Switzerland
  6. 6Department of Surgery, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario M4N 3M5, Canada
  7. 7Division General Internal Medicine, University Hospitals of Geneva, 1205 Geneva, Switzerland
  8. 8Alberta Health Services, Calgary, Alberta T1Y 6J4, Canada
  9. 9Divisions of Pulmonology and Medical Intensive Care, Stellenbosch University, Cape Town 7505, South Africa
  10. 10Departments of Internal Medicine and Biochemistry & Molecular Genetics, American University of Beirut Faculty of Medicine and Medical Center, Beirut 1107 2020, Lebanon
  11. 11Salt Lake City, Utah 84106, USA
  12. 12Ottawa, Ontario K2P 1C8, Canada
  13. 13Hatley, Quebec J0B 4B0, Canada
  14. 14Institute of Health and Society, Faculty of Medicine, University of Oslo, Oslo, Norway
  15. 15Division Clinical Epidemiology, University Hospitals of Geneva, 1205 Geneva, 1205, Switzerland
  1. Correspondence: R A C Siemieniuk reed.siemieniuk{at}medportal.ca

What you need to know

  • It is a longstanding cultural norm to provide supplemental oxygen to sick patients regardless of their blood oxygen saturation

  • A recent systematic review and meta-analysis has shown that too much supplemental oxygen increases mortality for medical patients in hospital

  • For patients receiving oxygen therapy, aim for peripheral capillary oxygen saturation (SpO2) of ≤96% (strong recommendation)

  • For patients with acute myocardial infarction or stroke, do not initiate oxygen therapy in patients with SpO2 ≥90% (for ≥93% strong recommendation, for 90-92% weak recommendation)

  • A target SpO2 range of 90-94% seems reasonable for most patients and 88-92% for patients at risk of hypercapnic respiratory failure; use the minimum amount of oxygen necessary

What is the best way to use oxygen therapy for patients with an acute medical illness? A systematic review published in the Lancet in April 2018 found that supplemental oxygen in inpatients with normal oxygen saturation increases mortality.1 Its authors concluded that oxygen should be administered conservatively, but they did not make specific recommendations on how to do it. An international expert panel used that review to inform this guideline. It aims to promptly and transparently translate potentially practice-changing evidence to usable recommendations for clinicians and patients.2 The panel used the GRADE framework and following standards for trustworthy guidelines.3

The panel asked;

  • In acutely ill patients, when should oxygen therapy be started? (What is the lower limit of peripheral capillary oxygen saturation (SpO2)?)

  • In acutely ill patients receiving oxygen therapy, how much oxygen should be given? (What is the upper limit of SpO2?)

The panel makes a strong recommendation for maintaining an oxygen saturation of no more than 96% in acutely ill medical patients (upper limit). The panel did not make a recommendation on when to start (the lower limit) for …

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Oxygen therapy for acutely ill medical patients: a clinical practice guideline (2024)

FAQs

What is the guideline for emergency oxygen use in adult patients? ›

Oxygen should be prescribed to achieve a target saturation of 94–98% for most acutely ill patients or 88–92% for those at risk of hypercapnic respiratory failure (tables 1–3). The target saturation should be written (or ringed) on the drug chart (guidance in fig 1).

What are the rules for oxygen therapy? ›

  • Keep your liquid oxygen unit upright at all times, never on its side.
  • Don't store your oxygen in an enclosed space, like a closet or trunk.
  • Be careful not to trip over the tubing. ...
  • Never use an extension cord to plug in your concentrator or plug anything else into the same outlet.
Dec 15, 2023

WHO guidelines for oxygen therapy? ›

Oxygen therapy is essential to counter hypoxaemia and many a times is the difference between life and death. This manual focuses on the availability and clinical use of oxygen therapy in children in health facilities by providing the practical aspects for health workers, biomedical engineers, and administrators.

Which guideline covers use of oxygen in an emergency? ›

ANZCOR Guideline 9.2. 10 - The Use of Oxygen in Emergencies.

What are the CMS guidelines for oxygen? ›

The Centers for Medicare & Medicaid Services (CMS) will cover the home use of oxygen as detailed in Section 240.2 of the CMS National Coverage Determinations Manual for beneficiaries who have arterial oxygen partial pressure measurements from 56 to 65 mmHg or oxygen saturation at or above 89% when they are enrolled in ...

What is the oxygen policy in hospitals? ›

Oxygen treatment is usually not necessary unless the SpO2 is less than 92%. That is, do not give oxygen if the SpO2 is ≥ 92%. Oxygen therapy (concentration and flow) may be varied in most circ*mstances without specific medical orders, but medical orders override these standing orders.

What are 5 rules that must be followed while oxygen is in use? ›

5 Safety Tips for Using Supplemental Oxygen Therapy
  • Don't Smoke Anywhere Near Oxygen.
  • Keep Oxygen Canisters Away From Open Flames.
  • Switch to a Non-Electric Razor.
  • Pass on Petroleum-Based Lotions and Creams.
  • How to Use Oxygen Safely.
Feb 5, 2024

What is oxygen protocol? ›

It provides a more efficient way to manage capital and is unique from other borrow lending protocols in three ways: Multiple uses of the same collateral. Oxygen enables you to generate yield on your portfolio through lending out your assets and borrowing other assets at the same time.

What are the nursing considerations for oxygen therapy? ›

11.1. OXYGEN THERAPY INTRODUCTION
  • Implement interventions to improve a patient's oxygenation status.
  • Correctly apply oxygen equipment.
  • Set flow rate using fixed and portable equipment.
  • Survey the environment for potential safety hazards.
  • Use pulse oximetry.
  • Assess patient response to oxygen therapy.

What are the guidelines for oxygenation? ›

For the otherwise healthy patient, oxygen saturation targets are generally at 92 to 98%. For patients with chronic hypercapnic conditions, target oxygen saturations are generally between 88 to 92%, with oxygen administration indicated at saturations below these levels.

In which conditions oxygen therapy is required? ›

Supplemental oxygen therapy helps people with COPD, COVID-19, emphysema, sleep apnea and other breathing problems get enough oxygen to function and stay well. Low blood oxygen levels (hypoxemia) can damage organs and be life-threatening. You may need oxygen therapy for life or temporarily.

What qualifies a patient for oxygen? ›

An arterial PO2 at or below 55 mm Hg or an arterial oxygen saturation at or below 88%, taken during exercise [defined as either the functional performance of the patient or a formal exercise test], for a patient who demonstrates an arterial PO2 at or above 56 mm Hg, or an arterial oxygen saturation at or above 89%, ...

What are the standards for oxygen therapy? ›

Oxygen should be prescribed to achieve a target saturation of 94–98% for most acutely ill patients or 88–92% or patient-specific target range for those at risk of hypercapnic respiratory failure (tables 1⇓⇓–4).

Who can administer oxygen in an emergency situation? ›

The FDA recognizes both emergency and prescription oxygen. Emergency devices may be used legally by a non-health care workplace first aider who has completed a course in oxygen administration.

How much oxygen should be given in an emergency situation? ›

If necessary, supplementary oxygen should be given concurrently by nasal prongs at 1-4 litres per minute to maintain an oxygen saturation of 88-92% or other specified target range. All patients requiring 35% or greater oxygen therapy should have their nebulised therapy by oxygen at a flow rate of 6-8 litres/minute.

When is a time you would use emergency oxygen on a patient? ›

Consider administering emergency oxygen for: An adult breathing fewer than 12 or more than 20 breaths per minute. A child breathing fewer than 15 or more than 30 breaths per minute. An infant breathing fewer than 25 or more than 50 breaths per minute.

What is the oxygen flow rate for a medical emergency? ›

Flow rates greater than 4 L/min may become uncomfortable over time, but 4–6 L/min delivering 36–44% oxygen should be adequate supplementation for most medical emergencies if the patient is breathing. For routine supplementation during minimal or moderate procedural sedation, 2 L/min or 28% oxygen is conventional.

How much oxygen can you give a patient with COPD in an emergency? ›

Oxygen therapy in the acute setting (in hospital)

Therefore, give oxygen at 24% (via a Venturi mask) at 2-3 L/minute or at 28% (via Venturi mask, 4 L/minute) or nasal cannula at 1-2 L/minute. Aim for oxygen saturation 88-92% for patients with a history of COPD until arterial blood gases (ABGs) have been checked .

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